Inhaled isoflurane sedation with the Anaconda device in extra-hospital medicine: feasibility study and prospects.




We conducted a monocentric prospective study on the feasibility and safety of sedation with a halogenated agent (isoflurane) in the outpatient setting, as it could be an interesting alternative

for the management of certain pathologies for patients requiring intubation and sedation.


We included 10 patients managed by a SMUR

(French SMUR are mobile emergency resuscitation trucks; fully equipped with resuscitation

devices) who required intubation followed by sedation as a primary intervention or for inter-hospital transfer.


The implementation of this technique appears simple to implement. There was no noticeable effect on hemodynamic status and there were no other adverse effects. Sedation was effective in 100% of cases (Ramsay score ≥ 5 for all patients at the 10th minute). Sedation with isoflurane administered by ANACONDA allows a simple, effective and safe sedation of intubated patients in out-of-hospital medicine (primary SMUR and medicalized transfers).


Hospital studies suggest that this technique could be useful in severe acute asthma, convulsive epileptic status and recovered cardiac arrest. Others studies are necessary to evaluate this technique, particularly in these 3 indications.



Key words: sedation isoflurane emergency extra-hospital medicine